The best-studied kratom compounds include mitragynine and 7-hydroxymitragynine.
Researchers are still learning about kratom’s short-term effects, long-term safety, and possible therapeutic uses. No kratom use is approved by the FDA as safe and effective medical treatment. People nevertheless report using it for pain, mental health concerns, or opioid withdrawal symptoms and cravings. Those reasons deserve understanding, but they do not remove product uncertainty or health risks.
